While more research is needed to understand how CBD oil is absorbed in the body, using CBD oil for sleep may allow for faster and more predictable absorption because it’s administered via mucosal dosing, says Mark H. Ratner, M.D., the chief science officer at Theralogix, a nutritional supplement company.
“Tinctures or oils that are placed under the tongue [may] provide absorption directly into the bloodstream and avoid the first pass effect,” he says, referring to what happens when a drug loses potency by the time it reaches its target or systemic circulation.
Meanwhile, some research suggests that orally ingested CBD oil is absorbed in the gastrointestinal tract. In fact, one small 2023 study found that CBD oil may be swallowed and absorbed in the gastrointestinal tract before mucosal absorption occurs . Meanwhile, a 2020 meta analysis in Pharmaceuticals found that orally-administered CBD oils and sprays are often unintentionally swallowed, and absorption rates may vary depending on whether an individual consumes CBD oil with a meal.
CBD oils are typically administered through a dropper, which makes it easy to know the dose you’re taking. This method also allows users to start with a low dose and work their way up as needed.
Potential Benefits of CBD Oil for Sleep
In addition to helping facilitate sleep, CBD can potentially help relieve symptoms of anxiety, depression, PTSD, opioid addiction and chronic pain.
By helping someone get more sleep, CBD oil can tangentially help improve other areas of life, according to Mikhail Heifitz, the chief operating officer of CBD product company Unabis. He notes that people who get better sleep may enjoy other benefits, such as:
- Increased focus during the day
- Weight control, as feeling more awake and energized can lead to increased physical activity and balanced eating habits
- Anxiety relief
Potential Risks and Side Effects
Potential side effects of CBD include sedation, sleep disturbances, anemia, diarrhea, fatigue and vomiting. CBD may also interact with other drugs you take.
“We suggest starting with small amounts of CBD, then slowly increasing the dosage to test how your body reacts and adjusting the dosage accordingly,” says Heifitz. You should also talk to your doctor about adding CBD to your wellness routine, especially if you take any other medications.
You may also have a reaction to other ingredients in CBD oil products, such as MCT oil, which is often used as a carrier oil in CBD products.
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