How Safe is CBD. Drug Interactions? Liver Effects? Doctor Jack Episode 3



How safe is CBD and what are studies showing? I also discuss my personal experiences with the safety of CBD. Thank you for …

27 Comments

  1. Saying “let’s jump straight into it” is useless filler. It is the opposite of getting to anything resembling a point. Please stop it. Just start 👍 you have lots of great content to share.

  2. Regular CBD user here, both oils and gummies. I had to get a Hep B and MMR vaccine for my new job at a health clinic. When is it safe restart taking CBD again? It’s been four days since I took the vaccines.

  3. My Dad is taking oxycodone 30mg , 4x /day for his severe cervical stenosis. How would you treat someone that is taking opioids and transition them to CBD Full Spectrum safely? No one wants to help my Dad. Can you please???

  4. I know a friend who od'd on CBD+THC and Delta 8 gummies. They took both a gummy and 0.5 ml of the tincture and had to go to ER the next day as it made them delirious and this was all from a proper CBD store…

  5. Hi Dr Jack! My uncle is scheduled for back surgery August 18th and has been having anxiety attacks lately so he wants to try CBD. I was thinking of recommending 750-1000 Broad Spectrum since he’s not comfortable with the THC in Full Spectrum. He wanted to know if he would have to stop taking it before his scheduled surgery. And what would you recommend he take after surgery since he does not want to get started on Oxycontin.

  6. Dr. Jack I am a newbie with CBD Gummies 25 mg broad-spectrum. I purchased these at a local store and Very impressed With the people in the image the store projected. . After I had paid for my gummy‘s one per day suggested the lady said do you take blood thinners and I do 75 mg of the generic for Plavix I have a stent 4 years in July. Of course I have Blood pressure .75 mg and the .81 aspirin Along with multivitamins and supplements immunity building. I neglected to say but I am proud of accumulating 80 years. No I have not discussed this with my cardiologist as suggested. I don’t feel any situation but I did on my own split the 25 mg gummy in half and my .75 mg Blood thinner in half we’re twice daily. No one told me to do that. I take this hoping to relieve myself of pain from stenosis sciatica piriformis muscle sacroiliac pain from my waist line and down it hurts I hurt. A huge part of my pain is the sit bones which I think it’s just the end of all of it. I am seeing an orthopedic doctor on Wednesday this week. I will declare what I am doing with her. I’ve listen to you for a few minutes and you seem pretty knowledgeable so with my information your thoughts on the blood thinner and blood pressure. The lady at the store said she had read articles where the CBD can actually lower blood pressure?? Thank you I hope to see you answer thank you

  7. Quick Q plz, Dr: What about taking CBD breaks? Especially for patients like myself, who take 200-300mgs/day AND are on BP meds and statin? I wonder if say a three day break would a) even be necessary at said dose and b) if three days is enough liver rebound-time.

    FWIW, I’ve been taking these doses of high-quality full spectrum, organic CBD for two years now and have yet to see any liver ramifications.

    Thanks. 🖖🏼

  8. The study of Jiang et al is mainly responsible for claims of CDB inhibition of liver enzymes (Drug Metab. Pharmacokinet. 2013;28(4):332-8). If one looks at plasma CBD levels after say, a 400 mg oral ingestion (a very large dose), the peak plasma CBD level in other studies was about 0.6 microMolar, which falls well short of the IC50 (concentration for half inhibition) reported by Jiang et al. (short by a range of approx. 7 to 33 percent of the IC50s). For a more typical, far lower dose of CBD, the inhibition would therefore be negligible. CBD narratives that are cautionary in this respect are found throughout the medical literature and popular press. These authors have been sloppy in failing to consider how CBD plasma levels relate to the reported IC50. The title of the Jiang article was not helpful, calling CBD a "potent inhibitor of P450 2C19". In a typical clinical context, it would be incorrect to call CBD a potent inhibitor of this enzyme. The observations that you bring up in this video are in agreement.

  9. Hi Dr. Jack, I am weaning myself off of Gabapentin. I was only on it for 3 weeks…Could I start taking CBD on my last week of weaning off? Also I am on Levothyroxine, if I take that every morning will that be ok since I would take the CBD at night for sleep…I will also be checking with my Dr. about the CBD and my other medications…

  10. Hi DrJack when you first said CBD use to me I cringed and told you no. I was tired of the feeling my pain meds was given me which was sleepy and from the bed to the couch. We discussed CBD again and after given it some thought and reading over the information you gave me to think about it and my own research I decided to give CBD a try . Oct 4 will be year I have been using CBD oils and I can contest it help me with my Broad range problems without that drug out feelings. Which I hated feeling like a zombie and not able to function. Plus reading and hearing of people dying off of Control pain pills. I did not want that for myself and certainly not strung out on pain killers. I can say I feel a difference using the CBD oil vs taken narcotics. I am able to function a little better mentally. On the Narcotics I could not. My depression and moods is even better on the CBD oil. Do I still have pain? Yes but it is Controlled when I use the CBD Oil and I am not feeling out of my mind. As a Patient on CBD oils I recommend it to those who.want an alternative to been hooked on narcotics.
    So far I have not had any side-effects from CBD oils and I just had a Physical nothing crazy came up from my use of CBD oils. As a matter of fact my Doctor asked me if it was helping with my sleep and depression. I told him yes.
    Did not mean to text Long. Just wanted to say I am almost a year with use and I do not feel like giving up on life like I did on narcotics….

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